Dream Big, Raise Standards

Lead Biosystems Engineering in the World

Our primary research program lies in the discovery and utilization of innovative engineering platforms based on biomaterials, multiscale fabrication, and biologically inspired design principle for controlling or promoting functions of living biological systems such as humans, animals, and plants. Using innovative micro- and nanoscale engineering tools developed in combination with traditional molecular, cell biology, and live cell imaging approaches, various physiological and disease processes in the living systems will be investigated as well as new tissue engineering technologies, therapeutics, and sensing/screening platforms will be developed. That is, the ultimate objective of our research is to develop multifunctional engineering systems for better understanding and engineering complex living systems as well as for various agriculture, biological, biomedical, environmental, and food applications for improving human life.


  • We are currently inviting applications for MS and PhD graduate students (BK fellowship)

  • Daun (MS degree) has accepted a researcher position at Jeonnam Bioindustry Foundation. Many congratulations! (November 2020)

  • Hyoseong officially joined our group. Warm welcome! (April 2020)

  • Our group has been awarded the research project funding from the National Research Foundation of Korea (NRF)! (October 2019)

  • Sunho's paper has been selected to feature on a front cover of ACS Applied Bio materials. Many congratulations! (September 2019)

  • Sunho's paper has been accepted to ACS Nano (IF: 13.906). Great works!  Many congratulations! (September 2019)       

  • Sunho's paper has been selected to feature on a front cover of Micromolecular Research. Many congratulations! (August 2019) 

  • Teaseong officially joined our group. Warm welcome! (July 2019)

  • Our group has been awarded the research project funding from the National Research Foundation of Korea (NRF)! (June 2019)

  Featured Publications

  • Nanoscale manufacturing as an enabling strategy for the design of smart food packaging systems. Food Packaging and Shelf Life 2020:26:100570.

  • Tendon-inspired nanotopographic scaffold for tissue regeneration in rotator cuff injuries. ACS Omega 2020:5:23:13913. [Press released in major media]

  • Graphene-chitosan hybrid dental implants with enhanced antibacterial and cell proliferation properties. Applied Sciences 2020:10:14:4888

  • Graphene oxide-assisted promotion of plant growth and stability. Nanomaterials 2020:10:4:758.

  • Evaluation of the osteogenic potential of stem cells in the presence of growth hormone under magnetic field stimulation. ACS Biomaterials Science & Engineering 2020:6:7:4141-4154.

  • Development and characterization of waste equine bone-derived calcium phosphate cements with human alveolar bone-derived mesenchymal stem cells. Connective Tissue Research 2020:1-12.

  • Editorial introduction to the special issue "Biomaterials and Biofabrication". Applied Sciences 2020:6388.

  • Cell-laden thermosensitive chitosan hydrogel bioinks for 3D bioprinting applications. Applied Science 2020:10:7:2455.

  • Lithographically-fabricated HA-Incorporated PCL nanopatterned patch for tissue engineering. Applied Sciences 2020:10:7:2398.

  • Hydrogel nanospike patch as a flexible anti-pathogenic scaffold for regulating stem cell behavior. ACS NANO 2019:13:10:11181-11193. [Press released in major media]

  • Graphene-layered eggshell membrane as a flexible and functional scaffold for enhanced proliferation and differentiation of stem cells. ACS Applied Bio Materials 2019:2:10:4242-4248. (Selected as a Cover Article) [Press released in major media]

  • 3D Microfluidic bone TME comprised of hydroxyapatite/fibrin composite. Frontiers in Bioengineering and Biotechnology 2019:7:168.

  • Bioengineered short carbon nanotubes as tumor-targeted carriers for biomedical imaging 2019:27:833-838. (Selected as a Cover Article)

  • Lipid-hydrogel-nanostructure hybrids as robust biofilm-resistant polymeric materials. ACS Macro Letters 2019:8:64. [Press released in major media]

  • Leaf-inspired micro- and nanoengineered surfaces for controlled hydrophilic and hydrophobic properties. Macromolecular Research 2019:27:2092-7673.

  • Engineering nanowrinkled microfibers composed of eggshell membrane and graphene. Materials Letters 2018:15:78-81.

  • Effect of topographical feature size on the trend of cell behaviors. IEEE Transactions on Nanotechnology 2018:17:377-380.

  • Controlled extracellular topographical and chemical cues for acceleration of neuronal development. Journal of Industrial and Engineering Chemistry 2018:61:65-70.

  • Engineering lotus leaf-inspired micro- and nanostructures for the manipulation of functional engineering platforms. Journal of Industrial and Engineering Chemistry 2018:61:39-52.

  • Neurogenic differentiation of human dental pulp stem cells on graphene-polycaprolactone hybrid nanofibers. Nanomaterials 2018:5:554. 

  • Iron oxide nanoparticle-incorporated alginate capsules as magnetic field-assisted potential delivery platforms for agriculture pesticides and biocontrol agents. Journal of Biosytems Engineering 2017:42:323-329. (Selected as a Cover Article)

  • Directional matrix nanotopography with varied sizes for engineering wound healing. Advanced Healthcare Materials 2017:6:19

  • Eggshell membrane: review and impact on engineering. Biosystems Engineering 2016:151:446-463. (Selected as one of Most Downloaded Biosystems Engineering Articles)

  • ​Hierarchically micro- and nanopatterned topographical cues for modulation of cellular structure and function. IEEE Transactions on Nanobioscience 2016:15:835-842. (Selected as Popular Documents)

  • Engineering structure and function of mesenchymal stem cells by suspended large area graphene nanopatterns. 2D Materials 2016:3:035013. [Press released in major media]

  • Microfluidic vascularized bone tissue model with hydroxyapatite-incorporated extracellular matrix. Lab on a Chip 2015:15:3984-3988. (Selected as a Cover Article) [Press released in major media]

  • Bio-inspired configurable multiscale extracellular matrix-like structures for functional alignment and guided orientation of cells. Biomaterials 2015:69: 158-164.

  • Latent progenitor cells as potential regulators for tympanic membrane regeneration. Scientific Reports 2015:3:11542. 

  • Monolayer graphene-directed growth and neuronal differentiation of mesenchymal stem cells. Journal of Biomedical Nanotechnology 2015 11:2021-2033.

  • In situ hybridization of carbon nanotubes with bacterial cellulose for three-dimensional hybrid bioscaffolds. Biomaterials 2015:58:83-102.

  • Multiscale patterned transplantable stem cell patches for bone tissue regeneration. Biomaterials 2014:35:9058-9067. (Samsung HumanTech Paper Award from the Samsung Electronics, 2014; Selected as ‘This Week’s Top Story’ from the Extracellular Matrix News, 2014) 

  • Biologically inspired micro- and nanoengineering systems for functional and complex tissues. Tissue Engineering: Part A 2014:20:2127-2130. (Invited as Inaugural Young Investigator Council Special Issue) 

  • Designing nanotopographical density of extracell ular matrix for controlled morphology and function of human mesenchymal stem cells. Scientific Reports 2013:3: doi:10.1038/srep03552.  (Young Scientist Award from the Korean and Japanese Society for Biomaterials, 2012; Award for Young Plenary Speaker from TERMIS-AP Conference, 2013) [Press released in major media such as Dong-A Ilbo, YTN, YTN science. Selected in the top 5% article ranked by Altmetric]

  • Synergistic effects of nanotopography and co-culture with endothelial cells on osteogenesis of mesenchymal stem cells Biomaterials 2013:34:7257-7268. (Outstanding Research Award from the Korean Tissue Engineering and Regenerative Medicine Society, 2013; Highlighted in Nanomedicine 2013:8(11):1743-1749, 2013)

  • Bioactive effects of graphene oxide cell culture substratum on structure and function of human adipose-derived stem cells. Journal of Biomedical Materials Research: Part A 2013:101A:3520-3530. (Selected as a Cover Article)

  • Graphene-incorporated chitosan substrata for promoting adhesion and differentiation of stem cells. Journal of Materials Chemistry B (as Communication) 2013:1:933-938. (Outstanding Research Award from the Korean Tissue Engineering and Regenerative Medicine Society, 2012; Selected as One of the Most Read Articles (top ranked) in JMC-B in January and February, 2013)

  • Charged nanomatrices as efficient platforms for modulating cell adhesion and shape. Tissue Engineering Part C: Methods, 2012:18(12):913-923. (Selected as a Cover Article and a Featured Article)

  • Topographical extracellular matrix cues on anticancer drug-induced cytotoxicity in stem cells. Journal of Biomedical Materials Research: Part B - Applied Biomaterials 2015:106:6:1320-1327 (Selected as a Featured Article)

  • Biologically inspired micro- and nanoengineering systems for functional and complex tissues. Tissue Engineering: Part A 2014:20:2127-2130. (Invited as Inaugural Young Investigator Council Special Issue)



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