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Dream Big, Raise Standards
Lead Biomedical and Agricultural Engineering in the World

Our primary research program lies in the discovery and utilization of innovative engineering platforms based on biomaterials, multiscale fabrication, and biologically inspired design principle for controlling or promoting functions of living biological systems such as humans, animals, and plants. Using innovative micro- and nanoscale engineering tools developed in combination with traditional molecular, cell biology, and live cell imaging approaches, various physiological and disease processes in the living systems will be investigated as well as new tissue engineering technologies, therapeutics, and sensing/screening platforms will be developed. That is, the ultimate objective of our research is to develop multifunctional engineering systems for better understanding and engineering complex living systems as well as for various agriculture, biological, biomedical, environmental, and food applications for improving human life.

   News​​

  • We are currently inviting applications for MS and PhD graduate students (BK fellowship)

  • Mahpara's paper has been accepted to Small (IF: 13). Great works! Many congratulations! (July 2024)

  • Dream won the excellent paper presentation award at The 12th World Biomaterials Congress. Many congratulations! (May 2024)​

  • Woochan won the excellent paper presentation award at The Korean Society of Industrial and Engineering Chemistry. Many congratulations! (May 2024)

  • Dr. Sangbae Park has been appointed as a professor at Seoul National University. Many congratulations! (March 2024)

  • Dr. Sunho Park has been appointed as a professor at Pusan National University. Many congratulations! (March 2024)

  • Woochan won the excellent paper presentation award at The Korean Society of Industrial and Engineering Chemistry. Many congratulations! (November 2023)

  • Sunho won the excellent paper presentation award at The Korean Society of Industrial and Engineering Chemistry. Many congratulations! (November 2023)

  • Sunho's paper has been accepted to Biomaterials (IF: 15.304). Great works! Many congratulations! (August 2023)

  • Sunho won the excellent paper presentation award at The Korean Society of Industrial and Engineering Chemistry. Many congratulations! (May 2023)

  • Woochan won the excellent paper presentation award at The Korea Socierty for Agricultural Machinery. Many congratulations! (April 2023)

  • Sangbae won the excellent paper presentation award at The Korea Socierty for Agricultural Machinery. Many congratulations! (April 2023)

  • Yonghyun won the excellent paper presentation award at The Korean Society for Biomaterials. Many congratulations! (March 2023)

  • Jinu, Duhee officially joined our group. Warm welcome! (March 2023)

  • ​Jeongryun officially joined our group. Warm welcome! (March 2023)

  • Sanbae Park, Ph.D. officially joined our group. Warm welcome! (March 2023)

  • Yonghyun won the excellent poster presentation award at the conference of The College of Agriculture and Life Sciences, Chonnam National University (November 2022)

  • Sunho won the excellent poster presentation award at The Organoid Society. Many congratulations! (November 2022)

  • Mahpara won the excellent paper presentation award at The Korea Socierty for Agricultural Machinery. Many congratulations! (November 2022)

  • Woochan won the academic encouragement award at The Korean Orthopaedic Association. Many congratulations! (October 2022)

  • Yonghyun won the academic encouragement award at The Korean Orthopaedic Association. Many congratulations! (October 2022)

  • Sunho won the young scientist award at The Korean Socienty for Biomaterials. Many congratulations! (September 2022)

  • Yonghyun's paper has been accepted to Bioengineering Translational Medicine (IF: 10.711). Great works! Many congratulations! (June 2022)

  • Mahpara's paper has been accepted to Journal of Nanobiotechnology (IF: 10.435). Great works! Many congratulations! (May 2022)

  • Yonghyun won the excellent poster presentation award at The Korean Society of Industrial and Engineering Chemistry Conference (KSIEC). Many congratulations! (May 2022)

  • Sunho won the Ph.D. excellent thesis award at The Korean Society of Mechanical Engineers. Many congratulations! (April 2022)

  • Yonghyun won the excellent paper presentation award at The Korean Society of Mechanical Engineers. Many congratulations! (April 2022)

  • Woochan's paper has been accepted to Bioactive Materials (IF: 14.593). Great works! Many congratulations! (March 2022)

  • Woochan's paper has been accepted to Nano Letters (IF: 11.189). Great works! Many congratulations! (Februray 2022)

  • Yonghyun won the BK21 Fellowship (five million won). Many congratulations! (March 2022)

  • Sunho got a Ph.D. degree. Many congratulations! (February 2022)

  • Shinyull officially joined our group. Warm welcome! (October 2021)

  Featured Publications​

  • Transplantable stem cell nanobridge scaffolds for accelerating articular cartilage regeneration. Biomaterials 2023:122287. [Press released in major media]

  • Graphene Hybrid Inner Ear Organoid with Enhanced Maturity. Nano Letters 2023:23(12):5573-5580. [Press released in major media]

  • Engineering considerations of iPSC-based personalized medicine. Biomaterials Research 2023:27(67).

  • Therapeutic strategies and enhanced production of stem cell-derived exosomes for tissue regeneration. Tissue Engineering Part B: Reviews 2022. (Selected as a cover article)

  • Eggshell membrane-incorporated cell friendly tough hydrogels with ultra-adhesive property. Colloids and Surfaces B: Biointerfaces 2023:223:113156. (Selected as a cover article)

  • Tissue engineered tendon nano-constructs for repair of chronic rotator cuff tears in large-animal models. Bioengineering & Translational Medicine 2022:e10376:1-14. [Press released in major media]

  • Engineering plants with carbon nanotubes: a sustainable agriculture approach. Journal of Nanobiotechnology 2022:20:275.

  • Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration. Bioactive Materials 2023:19:50-74.

  • Biodegradable and flexible nanoporous films for design and fabrication of smart food packaging systems. Nano Letters 2022:22(8):3480–3487. (Selected as a cover article) [Press released in major media]

  • A freezing and thaw method for fabrication of small gelatin nanoparticles with stable size distributions for biomedical applications. Tissue Engineering and Regenerative Medicine 2021:1-7. [Press released in major media]

  • Plasma-assisted multiscale topographic scaffolds for soft and hard tissue regeneration. npj Regenerative Medicine 2021:6:1:1-13. [Press released in major media]

  • Eggshell membrane as a bioactive agent in polymeric nanotopographic scaffolds for enhanced bone regeneration. Biotechnology and Bioengineering 2021:1-14. [Press released in The Academic Times] (Selected as a cover article)

  • Nanoscale manufacturing as an enabling strategy for the design of smart food packaging systems. Food Packaging and Shelf Life 2020:26:100570.

  • Synergistic effects of gelatin and nanotopographical patterns on biomedical PCL patches for enhanced mechanical and adhesion properties. Journal of the Mechanical Behavior of Biomedical Materials 2020:104167.

  • Tendon-inspired nanotopographic scaffold for tissue regeneration in rotator cuff injuries. ACS Omega 2020:5:23:13913. [Press released in major media]

  • Graphene oxide-assisted promotion of plant growth and stability. Nanomaterials 2020:10:4:758.

  • Hydrogel nanospike patch as a flexible anti-pathogenic scaffold for regulating stem cell behavior. ACS NANO 2019:13:10:11181-11193. [Press released in major media]

  • Graphene-layered eggshell membrane as a flexible and functional scaffold for enhanced proliferation and differentiation of stem cells. ACS Applied Bio Materials 2019:2:10:4242-4248. (Selected as a cover article) [Press released in major media]

  • 3D Microfluidic bone TME comprised of hydroxyapatite/fibrin composite. Frontiers in Bioengineering and Biotechnology 2019:7:168.

  • Bioengineered short carbon nanotubes as tumor-targeted carriers for biomedical imaging 2019:27:833-838. (Selected as a cover article)

  • Lipid-hydrogel-nanostructure hybrids as robust biofilm-resistant polymeric materials. ACS Macro Letters 2019:8:64. [Press released in major media]

  • Leaf-inspired micro- and nanoengineered surfaces for controlled hydrophilic and hydrophobic properties. Macromolecular Research 2019:27:2092-7673.

  • Engineering nanowrinkled microfibers composed of eggshell membrane and graphene. Materials Letters 2018:15:78-81.

  • Effect of topographical feature size on the trend of cell behaviors. IEEE Transactions on Nanotechnology 2018:17:377-380.

  • Controlled extracellular topographical and chemical cues for acceleration of neuronal development. Journal of Industrial and Engineering Chemistry 2018:61:65-70.

  • Engineering lotus leaf-inspired micro- and nanostructures for the manipulation of functional engineering platforms. Journal of Industrial and Engineering Chemistry 2018:61:39-52.

  • Neurogenic differentiation of human dental pulp stem cells on graphene-polycaprolactone hybrid nanofibers. Nanomaterials 2018:5:554. 

  • Iron oxide nanoparticle-incorporated alginate capsules as magnetic field-assisted potential delivery platforms for agriculture pesticides and biocontrol agents. Journal of Biosytems Engineering 2017:42:323-329. (Selected as a cover article)

  • Directional matrix nanotopography with varied sizes for engineering wound healing. Advanced Healthcare Materials 2017:6:19

  • Eggshell membrane: review and impact on engineering. Biosystems Engineering 2016:151:446-463. (Selected as one of most downloaded Biosystems Engineering Articles)

  • ​Hierarchically micro- and nanopatterned topographical cues for modulation of cellular structure and function. IEEE Transactions on Nanobioscience 2016:15:835-842. (Selected as popular documents)

  • Engineering structure and function of mesenchymal stem cells by suspended large area graphene nanopatterns. 2D Materials 2016:3:035013. [Press released in major media]

  • Microfluidic vascularized bone tissue model with hydroxyapatite-incorporated extracellular matrix. Lab on a Chip 2015:15:3984-3988. (Selected as a cover article) [Press released in major media]

  • Bio-inspired configurable multiscale extracellular matrix-like structures for functional alignment and guided orientation of cells. Biomaterials 2015:69: 158-164.

  • Latent progenitor cells as potential regulators for tympanic membrane regeneration. Scientific Reports 2015:3:11542.

  • Monolayer graphene-directed growth and neuronal differentiation of mesenchymal stem cells. Journal of Biomedical Nanotechnology 2015 11:2021-2033.

  • In situ hybridization of carbon nanotubes with bacterial cellulose for three-dimensional hybrid bioscaffolds. Biomaterials 2015:58:83-102.

  • Multiscale patterned transplantable stem cell patches for bone tissue regeneration. Biomaterials 2014:35:9058-9067. (Samsung HumanTech Paper Award from the Samsung Electronics, 2014; Selected as ‘This Week’s Top Story’ from the Extracellular Matrix News, 2014) 

  • Biologically inspired micro- and nanoengineering systems for functional and complex tissues. Tissue Engineering: Part A 2014:20:2127-2130. (Invited as Inaugural Young Investigator Council Special Issue) 

  • Designing nanotopographical density of extracellular matrix for controlled morphology and function of human mesenchymal stem cells. Scientific Reports 2013:3: doi:10.1038/srep03552.  (Young Scientist Award from the Korean and Japanese Society for Biomaterials, 2012; Award for Young Plenary Speaker from TERMIS-AP Conference, 2013) [Press released in major media such as Dong-A Ilbo, YTN, YTN science. Selected in the top 5% article ranked by Altmetric]

  • Synergistic effects of nanotopography and co-culture with endothelial cells on osteogenesis of mesenchymal stem cells Biomaterials 2013:34:7257-7268. (Outstanding Research Award from the Korean Tissue Engineering and Regenerative Medicine Society, 2013; Highlighted in Nanomedicine 2013:8(11):1743-1749, 2013)

  • Bioactive effects of graphene oxide cell culture substratum on structure and function of human adipose-derived stem cells. Journal of Biomedical Materials Research: Part A 2013:101A:3520-3530. (Selected as a Cover Article)

  • Graphene-incorporated chitosan substrata for promoting adhesion and differentiation of stem cells. Journal of Materials Chemistry B (as Communication) 2013:1:933-938. (Outstanding Research Award from the Korean Tissue Engineering and Regenerative Medicine Society, 2012; Selected as One of the Most Read Articles (top ranked) in JMC-B in January and February, 2013)

  • Charged nanomatrices as efficient platforms for modulating cell adhesion and shape. Tissue Engineering Part C: Methods, 2012:18(12):913-923. (Selected as a Cover Article and a Featured Article)

  • Topographical extracellular matrix cues on anticancer drug-induced cytotoxicity in stem cells. Journal of Biomedical Materials Research: Part B - Applied Biomaterials 2015:106:6:1320-1327 (Selected as a Featured Article)

  • Biologically inspired micro- and nanoengineering systems for functional and complex tissues. Tissue Engineering: Part A 2014:20:2127-2130. (Invited as Inaugural Young Investigator Council Special Issue)

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